Pooran, A;
Booth, H;
Miller, RF;
Scott, G;
Badri, M;
Huggett, JF;
Rook, G;
... Dheda, K; + view all
(2010)
Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis.
BMC Pulmonary Medicine
, 10
, Article 7. 10.1186/1471-2466-10-7.
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Abstract
Previous health economic studies recommend either a dual screening strategy [tuberculin skin test (TST) followed by interferon-gamma-release assay (IGRA)] or a single one [IGRA only] for latent tuberculosis infection (LTBI), the former largely based on claims that it is more cost-effective. We sought to examine that conclusion through the use of a model that accounts for the additional costs of adverse drug reactions and directly compares two commercially available versions of the IGRA: the Quantiferon-TB-Gold-In-Tube (QFT-GIT) and T-SPOT.TB.
| Type: | Article |
|---|---|
| Title: | Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/1471-2466-10-7 |
| Publisher version: | http://dx.doi.org/10.1186/1471-2466-10-7 |
| Language: | English |
| Additional information: | © 2010 Pooran et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. PMCID: PMC2837635 |
| Keywords: | Contact Tracing, Cost-Benefit Analysis, Decision Trees, Enzyme-Linked Immunosorbent Assay, Great Britain, Health Care Costs, Humans, Incidence, Interferon-gamma, Mass Screening, Prevalence, Sensitivity and Specificity, Tuberculin Test, Tuberculosis, Pulmonary |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/162388 |
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