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Voxel similarity measures for 3D serial MR brain image registration

Holden, M; Hill, DLG; Denton, ERE; Jarosz, JM; Cox, TCS; Hawkes, DJ; (1999) Voxel similarity measures for 3D serial MR brain image registration. In: Kuba, A and Samal, M and ToddPokropek, A, (eds.) INFORMATION PROCESSING IN MEDICAL IMAGING, PROCEEDINGS. (pp. 472 - 477). SPRINGER-VERLAG BERLIN

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Abstract

We investigated 7 different similarity measures for rigid body registration of serial MR brain scans. To assess their accuracy we used a set of 33 clinical 3D serial MR images, manually segmented by a radiologist to remove deformable extra-dural tissue, and also simulated brain model data. For each measure we determined the consistency of registration transformations for both sets of segmented and unsegmented data. The difference images produced by registration with and without segmentation were visually inspected by two radiologists in a blinded study. We have shown that of the measures tested, those based on joint entropy produced the best consistency and seemed least sensitive to the presence of extra-dural tissue. For this data the difference in accuracy of these joint entropy measures, with or without brain segmentation, was within the threshold of visually detectable change in the difference images.

Type: Proceedings paper
Title: Voxel similarity measures for 3D serial MR brain image registration
Event: 16th International Conference on Information Processing in Medical Imaging (IPMI 99)
Location: VISEGRAD, HUNGARY
Dates: 1999-06-28 - 1999-07-02
ISBN: 3-540-66167-0
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: http://discovery.ucl.ac.uk/id/eprint/162036
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