UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Security and confidentiality approach for the Clinical E-Science Framework (CLEF)

Kalra, D.; Singleton, P.; Milan, J.; MacKay, J.; Detmer, D.; Rector, A.; Ingram, D.; (2005) Security and confidentiality approach for the Clinical E-Science Framework (CLEF). Methods of Information in Medicine , 44 (2) pp. 193-197. Green open access


Download (999kB)


Objectives: CLEF is an MRC sponsored project in the E-Science programme that aims to establish methodologies and a technical infrastructure for the next generation of integrated clinical and bioscience research. Methods: The heart of the CLEF approach to this challenge is to design and develop a pseudonymised repository of histories of cancer patients that can be accessed by researchers. Robust mechanisms and policies have been developed to ensure that patient privacy and confidentiality are preserved while delivering a repository of such medically rich information for the purposes of scientific research. Results: This paper summarises the overall approach adopted by CLEF to meet data protection requirements, including the data flows, pseudonymisation measures and additional monitoring policies that are currently being developed. Conclusion: Once evaluated, it is hoped that the CLEF approach can serve as a model for other distributed electronic health record repositories to be accessed for research.

Type: Article
Title: Security and confidentiality approach for the Clinical E-Science Framework (CLEF)
Identifier: PMID: 15924174
Open access status: An open access version is available from UCL Discovery
Publisher version: http://www.schattauer.de/z/30_zeitschriften_ihv.as...
Language: English
Keywords: Electronic health records, data repository, pseudonymisation, grid computing, access control
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Health Informatics > CHIME
URI: http://discovery.ucl.ac.uk/id/eprint/1593
Downloads since deposit
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item