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Comparison and evaluation of rigid, affine, and nonrigid registration of breast MR images

Denton, ER; Sonoda, LI; Rueckert, D; Rankin, SC; Hayes, C; Leach, MO; Hill, DL; (1999) Comparison and evaluation of rigid, affine, and nonrigid registration of breast MR images. J COMPUT ASSIST TOMOGR , 23 (363-8715) pp. 800-805.

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Abstract

PURPOSE: A new nonrigid registration method, designed to reduce the effect of movement artifact in subtraction images from breast MR, is compared with existing rigid and affine registration methods. METHOD: Nonrigid registration was compared with rigid and affine registration methods and unregistered images using 54 gadolinium-enhanced 3D breast MR data sets. Twenty-seven data sets had been previously reported normal, and 27 contained a histologically proven carcinoma. The comparison was based on visual assessment and ranking by two radiologists. RESULTS: When analyzed by two radiologists independently, all three registration methods gave better-quality subtraction images than unregistered images (p < 0.01), but nonrigid registration gave significantly better results than the rigid and affine registration methods (p < 0.01). There was no significant difference between rigid and affine registration methods. CONCLUSION: Nonrigid registration significantly reduces the effects of movement artifact in subtracted contrast-enhanced breast MRI. This may enable better visualization of small tumors and those within a glandular breast

Type: Article
Title: Comparison and evaluation of rigid, affine, and nonrigid registration of breast MR images
Additional information: DA - 19991027
Keywords: Adult, Aged, Algorithms, Breast, pathology, Comparative Study, Contrast Media, Female, Gadolinium DTPA, diagnostic use, Humans, Magnetic Resonance Imaging, instrumentation, methods, statistics & numerical data, Middle Aged, Observer Variation, Research Support, Non-U.S.Gov't, Statistics, Nonparametric
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: http://discovery.ucl.ac.uk/id/eprint/157600
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