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The measurement of blood flow waveforms from X-ray angiography. Part 1: Principles of the method and preliminary validation.

Brunt, JN; Wicks, DA; Hawkes, DJ; Seifalian, AM; du Boulay, GH; Colchester, AF; Wallis, A; (1992) The measurement of blood flow waveforms from X-ray angiography. Part 1: Principles of the method and preliminary validation. Proc Inst Mech Eng H , 206 (2) pp. 73-85. 10.1243/PIME_PROC_1992_206_270_02.

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Abstract

The principles and implementation of a method for measurement of blood flow waveforms from X-ray angiography are described. Contrast medium mass values are obtained at multitudinous positions along individual vessels and from numerous images in a time sequence. These values are represented as a matrix of grey levels in a parametric image. This image is normalized to represent contrast medium concentration, and the movement over time of isoconcentration portions of the contrast bolus is recovered to determine blood flow. Preliminary validation has been undertaken using parametric images generated in two ways: synthesis from a computer model of vascular pulsatile flow and analysis of cine-angiograms of physical models (plastic and perspex tubes) carrying known pulsatile flows. Two distinct methods for interrogation of parametric images by digital image processing were employed; both provided accurate flow measurements.

Type: Article
Title: The measurement of blood flow waveforms from X-ray angiography. Part 1: Principles of the method and preliminary validation.
Location: England
DOI: 10.1243/PIME_PROC_1992_206_270_02
Keywords: Blood Flow Velocity, Cineangiography, Computer Simulation, Contrast Media, Image Processing, Computer-Assisted, Models, Cardiovascular, Pulsatile Flow
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: http://discovery.ucl.ac.uk/id/eprint/157581
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