Barrington, C;
Pezic, D;
Hadjur, S;
(2017)
Chromosome structure dynamics during the cell cycle: a structure to fit every phase.
The EMBO Journal
, 36
(17)
, Article e201798014. 10.15252/embj.201798014.
Preview |
Text
embj.201798014.full.pdf - Published Version Download (1MB) | Preview |
Abstract
Chromosomes undergo dramatic morphological changes as cells advance through the cell cycle. Using powerful molecular and computational methods, several recent studies revealed an outstanding complexity of continuous structural changes accompanying cell cycle progression. In agreement with cell division being a fundamental cellular process, characteristic features of cell cycle stage‐specific genome structure are conserved from yeast to mouse. These studies further shine light on the critical roles that SMC complexes, already well known as fundamental regulators of chromosome topology, have in orchestrating structural dynamics throughout the cell cycle.
| Type: | Article |
|---|---|
| Title: | Chromosome structure dynamics during the cell cycle: a structure to fit every phase |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.15252/embj.201798014 |
| Publisher version: | http://dx.doi.org/10.15252/embj.201798014 |
| Language: | English |
| Additional information: | © 2017 The Authors. Published under the terms of the CC BY 4.0 license |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Cancer Bio |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1573279 |
Archive Staff Only
 |
View Item |
