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Relaxation and Guided Imagery Significantly Reduces Androgen Levels and Distress in Polycystic Ovary Syndrome: Pilot Study

Barry, JA; Leite, N; Sivarajah, N; Keevil, B; Owen, L; Miranda, LCS; Qu, F; (2017) Relaxation and Guided Imagery Significantly Reduces Androgen Levels and Distress in Polycystic Ovary Syndrome: Pilot Study. Contemporary Hypnosis and Integrative Therapy , 32 (1) pp. 21-29. Green open access

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Abstract

AIM: Women with polycystic ovary syndrome (PCOS) often have elevated levels of the androgen testosterone, and are at increased risk of anxiety and depression. This study aimed to use psychological relaxation with guided imagery to decrease androgen levels and improve mood in PCOS. METHODS: Repeated-measures. Thirteen women with PCOS underwent six weekly treatment sessions, and a follow-up session, of calming breathing, muscle relaxation, and guided imagery. The main outcome measures were mood and quality of life (QoL) – assessed using validated questionnaires – and hormones, which were assayed in serum using tandem mass spectrometry. RESULTS: There was a small but statistically significant reduction in DHEAS from before to after Week 1 (p <.044) and from before to after Week 6 (p <.001). From before to after Week 6 there were also small but statistically significant reductions in androstenedione (p <.010) and cortisol (p <.003). From Week 1 to Week 6 there was a significant reduction in anxiety (p <.037). There was a significant improvement in depression from Week 1 to Week 6 (p <.034) and from Week 1 to follow-up (p <.011). There were no significant changes in free or total testosterone, nor in QoL. CONCLUSIONS: This is the first study to use a relaxation programme to reduce adrenal androgens in PCOS.

Type: Article
Title: Relaxation and Guided Imagery Significantly Reduces Androgen Levels and Distress in Polycystic Ovary Syndrome: Pilot Study
Open access status: An open access version is available from UCL Discovery
Publisher version: https://www.bscah.com/journal-ch-it
Language: English
Additional information: Copyright © 2017 British Society of Clinical and Academic Hypnosis. Published by Crown House Publishing Ltd. This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Relaxation; androgen; depression; anxiety; polycystic ovary syndrome
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Inst for Women's Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Inst for Women's Health > Reproductive Health
URI: http://discovery.ucl.ac.uk/id/eprint/1567722
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