UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Autism Spectrum Disorders in Adult Outpatients with Obsessive Compulsive Disorder in the UK

Wikramanayake, M; Mandy, W; Shahper, S; Kaur, S; Kolli, S; Osman, S; Reid, J; ... Fineberg, N; + view all (2018) Autism Spectrum Disorders in Adult Outpatients with Obsessive Compulsive Disorder in the UK. International Journal of Psychiatry in Clinical Practice , 22 (1) 54 -62. 10.1080/13651501.2017.1354029. Green open access

[thumbnail of Wikramanayake_Autism_Spectrum_Disorders.pdf]
Preview
Text
Wikramanayake_Autism_Spectrum_Disorders.pdf - Accepted Version

Download (1MB) | Preview

Abstract

BACKGROUND: Patients with obsessive compulsive disorder (OCD) frequently show traits of autism spectrum disorders (ASD). This is one of the first studies to explore the clinical impact of the overlap between OCD and ASD as a categorical diagnosis. METHODS: A cross-sectional survey in 73 adult outpatients with DSM-IV OCD. Autistic traits were measured using the Autism-Spectrum Quotient (AQ). A clinical estimate ASD diagnosis was made by interview using DSM-IV-TR criteria. OCD patients with and without autistic traits or ASD were compared on demographic and clinical parameters and level of OCD treatment-resistance based on treatment history. RESULTS: Thirty-four (47%) patients scored above the clinical threshold on the AQ (> =26) and 21 (27.8%) met diagnostic criteria for ASD. These diagnoses had not been made before. Patients with autistic traits showed a borderline significant increase in OCD symptom-severity (Yale-Brown Obsessive Compulsive Scale (Y-BOCS); p=.054) and significantly increased impairment of insight (Brown Assessment of Beliefs Scale; p=.01). There was a positive correlation between AQ and Y-BOCS scores (p =.04), but not with OCD treatment resistance. CONCLUSION: There is a high prevalence of previously undiagnosed ASD in patients with OCD. ASD traits are associated with greater OCD symptom-severity and poor insight.

Type: Article
Title: Autism Spectrum Disorders in Adult Outpatients with Obsessive Compulsive Disorder in the UK
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/13651501.2017.1354029
Publisher version: http://dx.doi.org/10.1080/13651501.2017.1354029
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Autism, Autism spectrum disorders, Autistic spectrum disorder, Autistic traits, Co-morbidity, Obsessive compulsive disorder
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: https://discovery.ucl.ac.uk/id/eprint/1567612
Downloads since deposit
845Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item