UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Why is the Peripheral Zone of the Normal Human Prostate High in ADC Value and T2-Weighted Signal Intensity?

Johnston, E; Bailey, C; Bonet-Carne, E; Pye, H; Heavey, S; Patel, D; Sridhar, A; ... Punwani, S; + view all (2017) Why is the Peripheral Zone of the Normal Human Prostate High in ADC Value and T2-Weighted Signal Intensity? Presented at: ISMRM 25th Annual Meeting & Exhibition, Honolulu, HI, USA.

Full text not available from this repository.

Abstract

The biophysical basis of MRI signal in the normal human prostate is uncertain, whereby the normal peripheral zone has high ADC values and returns high signal on T2-weighted imaging. In this study, we use MRI in combination with quantitative digital histopathology to offer an explanation. Paired scans were performed at 3T on a human prostate, prior to and following prostatectomy and changes in zonal morphology and MRI characteristics were measured. The peripheral zone collapsed and reduced in T2 signal intensity and ADC value ex-vivo. Digital histopathological analysis suggested the peripheral zone stores more ejaculatory fluid than the transition zone.

Type: Conference item (Presentation)
Title: Why is the Peripheral Zone of the Normal Human Prostate High in ADC Value and T2-Weighted Signal Intensity?
Event: ISMRM 25th Annual Meeting & Exhibition
Location: Honolulu, HI, USA
Dates: 22 - 27 April 2017
Publisher version: http://www.ismrm.org/17/program_files/TP07.htm
Language: English
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Pathology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Metabolism and Experi Therapeutics
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: http://discovery.ucl.ac.uk/id/eprint/1559317
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item