UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Frequency and phenotype of circulating V alpha 24/V beta 11 double-positive natural killer T cells during hepatitis C virus infection

Lucas, M; Gadola, S; Meier, U; Young, NT; Harcourt, G; Karadimitris, A; ... Klenerman, P; + view all (2003) Frequency and phenotype of circulating V alpha 24/V beta 11 double-positive natural killer T cells during hepatitis C virus infection. J VIROL , 77 (3) 2251 - 2257. 10.1128/JVI.77.3.2251-2257.2003.

Full text not available from this repository.

Abstract

Natural killer T (NKT) cells are thought to be involved in innate responses against infection. We investigated one specific type of NKT cell, Valpha24/Vbeta11 double positive, in hepatitis C virus (HCV) infection. Lower frequencies of this population were detected in the blood of HCV PCR-positive patients than in controls. Unlike Valpha24/Vbeta11 NKT cells found in blood, those in the liver appeared to be recently activated.

Type:Article
Title:Frequency and phenotype of circulating V alpha 24/V beta 11 double-positive natural killer T cells during hepatitis C virus infection
DOI:10.1128/JVI.77.3.2251-2257.2003
Keywords:NKT CELLS, INTRAHEPATIC LYMPHOCYTES, CD1D TETRAMERS, IN-VIVO, ACTIVATION, LIVER, EXPANSION, IL-15

Archive Staff Only: edit this record