Guggenheim, JA;
Bargigia, I;
Farina, A;
Pifferi, A;
Dehghani, H;
(2016)
Time resolved diffuse optical spectroscopy with geometrically accurate models for bulk parameter recovery.
Biomedical Optics Express
, 7
(9)
p. 3784.
10.1364/BOE.7.003784.
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Abstract
A novel straightforward, accessible and efficient approach is presented for performing hyperspectral time-domain diffuse optical spectroscopy to determine the optical properties of samples accurately using geometry specific models. To allow bulk parameter recovery from measured spectra, a set of libraries based on a numerical model of the domain being investigated is developed as opposed to the conventional approach of using an analytical semi-infinite slab approximation, which is known and shown to introduce boundary effects. Results demonstrate that the method improves the accuracy of derived spectrally varying optical properties over the use of the semi-infinite approximation.
| Type: | Article |
|---|---|
| Title: | Time resolved diffuse optical spectroscopy with geometrically accurate models for bulk parameter recovery |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1364/BOE.7.003784 |
| Publisher version: | https://doi.org/10.1364/BOE.7.003784 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1550605 |
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