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Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941

Raynaud, FI; Eccles, SA; Patel, S; Alix, S; Box, G; Chuckowree, I; Folkes, A; ... Workman, P; + view all (2009) Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941. MOLECULAR CANCER THERAPEUTICS , 8 (7) pp. 1725-1738. 10.1158/1535-7163.MCT-08-1200.

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Type: Article
Title: Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941
DOI: 10.1158/1535-7163.MCT-08-1200
Keywords: Science & Technology, Life Sciences & Biomedicine, Oncology, PI3-KINASE P110-ALPHA INHIBITORS, PHOSPHOINOSITIDE 3-KINASES, PI3 KINASE, CANCER, PATHWAY, DERIVATIVES, MUTATIONS, PIK3CA, GLIOMA, ANGIOGENESIS
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1549381
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