Bucking, TM;
van den Berg, PJ;
Balabani, S;
Steenbergen, W;
Beard, PC;
Brunker, J;
(2017)
Acoustic resolution photoacoustic Doppler flowmetry using a transducer array: optimising processing for velocity contrast.
In: Oraevsky, AA and Wang, LV, (eds.)
Proceedings Volume 10064, Photons Plus Ultrasound: Imaging and Sensing 2017.
SPIE: San Francisco, CA, USA.
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Abstract
This work demonstrates the first measurements of blood flow velocity using photoacoustic flowmetry (PAF) employing a transducer array. The measurements were made in a flow phantom consisting of a tube (580 μm inner diameter) containing blood flowing steadily at physiological speeds ranging from 3 mm/s to 25 mm/s. Velocity measurements were based on the generation of two successive photoacoustic (PA) signals using two laser pulses with a wavelength of 1064 nm; the PA signals were detected using a 64-element transducer array with a -6 dB detection bandwidth of 11-17 MHz. We developed a processing pipeline to optimise a cross-correlation based velocity measurement method comprising the following processing steps: image reconstruction, filtering, displacement detection, and masking. We found no difference in flow detection accuracy when choosing different image reconstruction algorithms (time reversal, Fourier transformation, and delay-and-sum). High-pass filtering and wallfiltering were however found to be essential pre-processing steps in order to recover the correct displacement information. We masked the calculated velocity map based on the amplitude of the cross-correlation function in order to define the region of interest corresponding to highest signal amplitude. These developments enabled blood flow measurements using a transducer array, bringing PAF one step closer to clinical applicability.
| Type: | Proceedings paper |
|---|---|
| Title: | Acoustic resolution photoacoustic Doppler flowmetry using a transducer array: optimising processing for velocity contrast |
| Event: | Photons Plus Ultrasound: Imaging and Sensing 2017 |
| Location: | San Francisco, CA |
| Dates: | 29 January 2017 - 01 February 2017 |
| ISBN-13: | 9781510605701 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1117/12.2252939 |
| Publisher version: | http://dx.doi.org/10.1117/12.2252939 |
| Language: | English |
| Additional information: | This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Flowmetry, blood flow, photoacoustic, optoacoustic, Doppler, cross-correlation, transducer array, image processing, masking |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1547707 |
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