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Adherence to asthma medication and preferences for once-daily treatment: Importance of treatment intrusiveness and patient beliefs

Chapman, S; Dale, P; Svedsater, H; Stynes, G; Vyas, N; Price, D; Horne, R; (2016) Adherence to asthma medication and preferences for once-daily treatment: Importance of treatment intrusiveness and patient beliefs. Presented at: European Respiratory Society Congress 2016, London.

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Abstract

Patients with asthma who do not adhere to treatment may experience poor control, and subsequently need greater healthcare. In a post-hoc analysis, we studied relationships between treatment adherence, asthma control, beliefs about medication, treatment intrusiveness, healthcare seeking and preference for OD vs BD maintenance medication using validated scales (Medication Adherence Report Scale [MARS], Asthma Control Test [ACT], Beliefs about Medicine Questionnaire-Necessity Concerns Differential [BMQ-NCD], Asthma Treatment Intrusiveness Questionnaire [ATIQ]). Patients were aged 18–55 yrs with self-reported asthma, ≥1 maintenance medications, recruited from 5 European countries (N=1010). Asthma was poorly controlled or uncontrolled in 46.1% of patients (ACT≤15); median MARS score=3.40, showed that most patients reported some nonadherence. Most patients (73.5%) preferred OD medication that was as effective as their current medication over a slightly more effective BD medication. Self-reported nonadherence was associated with poorer asthma control (r=0.262, p<0.001) and increased HCP visits (r=–0.075, p<0.05). Nonadherence (MARS) and preference for OD treatment were associated with perceptions of treatment (BMQ-NCD) and treatment intrusiveness (ATIQ; Table). MARS Prefer OD treatment* BMQ NCD r=0.437, <0.001 6.886, <0.001 ATIQ r=–0.422, <0.001 2.689, <0.01 *Test statistic Results suggest a complex inter-relationship between patients' beliefs about medication, intrusiveness, treatment adherence and preference for OD vs BD maintenance medication that all impact asthma control, and should be considered when evaluating treatment options. Funded by GSK (GHO-10-4705).

Type: Conference item (Presentation)
Title: Adherence to asthma medication and preferences for once-daily treatment: Importance of treatment intrusiveness and patient beliefs
Event: European Respiratory Society Congress 2016
Location: London
Dates: 03 September 2016 - 07 September 2016
DOI: 10.1183/13993003.congress-2016.PA5018
Publisher version: https://erscongress.org/programme-2016.html
Additional information: European Respiratory Journal 2016 48: PA5018; DOI: 10.1183/13993003.congress-2016.PA5018
Keywords: Asthma - management, Education, Treatments
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Practice and Policy
URI: http://discovery.ucl.ac.uk/id/eprint/1547599
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