Kang, J; Reynolds, NL; Tyrrell, C; Dorin, JR; Macmillan, D; (2009) Peptide thioester synthesis through N -> S acyl-transfer: application to the synthesis of a beta-defensin. ORG BIOMOL CHEM , 7 (23) 4918 - 4923. 10.1039/b913886b.
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Peptide thioesters readily prepared through N -> S acyl transfer of a specific C-terminal motif provide access to biologically active mini-proteins using native chemical ligation.
|Title:||Peptide thioester synthesis through N -> S acyl-transfer: application to the synthesis of a beta-defensin|
|Keywords:||CPE AUTOACTIVATING UNIT, LIGATION, BETA-DEFENSIN-3, GENERATION, PROTEINS, SHIFT|
|UCL classification:||UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Chemistry|
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