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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Anastasiou, D; Yu, Y; Israelsen, WJ; Jiang, J-K; Boxer, MB; Hong, BS; Tempel, W; ... Heiden, MGV; + view all (2012) Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. NATURE CHEMICAL BIOLOGY , 8 (10) pp. 839-847. 10.1038/NCHEMBIO.1060.

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Type: Article
Title: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
DOI: 10.1038/NCHEMBIO.1060
Keywords: Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, CANCER-CELL METABOLISM, TUMOR-GROWTH, NUCLEAR TRANSLOCATION, THYROID-HORMONE, BINDING PROTEIN, ISOFORM, FRUCTOSE-1,6-BISPHOSPHATE, ISOZYME, INHIBITION, CONVERSION
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1539742
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