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Tumour microenvironment factors shaping the cancer metabolism landscape

Anastasiou, D; (2017) Tumour microenvironment factors shaping the cancer metabolism landscape. British Journal of Cancer , 116 (3) pp. 277-286. 10.1038/bjc.2016.412. Green open access

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Abstract

Cancer cells exhibit metabolic alterations that distinguish them from healthy tissues and make their metabolic processes susceptible to pharmacological targeting. Although typical cell-autonomous features of cancer metabolism have been emerging, it is increasingly appreciated that extrinsic factors also influence the metabolic properties of tumours. This review highlights evidence from the recent literature to discuss how conditions within the tumour microenvironment shape the metabolic character of tumours.

Type: Article
Title: Tumour microenvironment factors shaping the cancer metabolism landscape
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/bjc.2016.412
Publisher version: http://doi.org/10.1038/bjc.2016.412
Language: English
Additional information: © The Author(s) named above 2017. This work is licensed under the Creative Commons Attribution-Non-Commercial-Share Alike 4.0 International License. To view a copy of this license, visit http:// creativecommons.org/licenses/by-nc-sa/4.0/
Keywords: Tumour microenvironment; cancer metabolism; cancer cell metabolism; tumour metabolism; metabolism; metabolic profile
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1538955
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