Koukou, V;
Martini, N;
Fountos, G;
Michail, C;
Sotiropoulou, P;
Bakas, A;
Kalyvas, N;
... Nikiforidis, G; + view all
(2017)
Dual energy subtraction method for breast calcification imaging.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
, 848
pp. 31-38.
10.1016/j.nima.2016.12.034.
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Abstract
The aim of this work was to present an experimental dual energy (DE) method for the visualization of microcalcifications (μCsμCs). A modified radiographic X-ray tube combined with a high resolution complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) X-ray detector was used. A 40/70 kV spectral combination was filtered with 100 μmμm cadmium (Cd) and 1000 μmμm copper (Cu) for the low/high-energy combination. Homogenous and inhomogeneous breast phantoms and two calcification phantoms were constructed with various calcification thicknesses, ranging from 16 to 152 μmμm. Contrast-to-noise ratio (CNR) was calculated from the DE subtracted images for various entrance surface doses. A calcification thickness of 152 μmμm was visible, with mean glandular doses (MGD) in the acceptable levels (below 3 mGy). Additional post-processing on the DE images of the inhomogeneous breast phantom resulted in a minimum visible calcification thickness of 93 μmμm (MGD=1.62 mGy). The proposed DE method could potentially improve calcification visibility in DE breast calcification imaging.
| Type: | Article |
|---|---|
| Title: | Dual energy subtraction method for breast calcification imaging |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.nima.2016.12.034 |
| Publisher version: | http://dx.doi.org/10.1016/j.nima.2016.12.034 |
| Language: | English |
| Additional information: | Copyright © 2016 Elsevier B.V. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Keywords: | Breast imaging; Dual energy; Calcifications; X-rays; Post-processing |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1534522 |
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