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Diffusion-based tractography in neurological disorders: concepts, applications, and future developments

Ciccarelli, O; Catani, M; Johansen-Berg, H; Clark, C; Thompson, A; (2008) Diffusion-based tractography in neurological disorders: concepts, applications, and future developments. LANCET NEUROL , 7 (8) 715 - 727.

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Abstract

Diffusion-based tractography enables the graphical reconstruction of the white matter pathways in the brain and spinal cord of living humans. This technique has many potential clinical applications, including the investigation of stroke, multiple sclerosis, epilepsy, neurodegenerative diseases, and spinal cord disorders, and it enables hypotheses to be tested that could not previously be considered in living humans. This Review will outline the limitations of tractography, describe its current clinical applications in the most common neurological diseases, and highlight future opportunities.

Type: Article
Title: Diffusion-based tractography in neurological disorders: concepts, applications, and future developments
Keywords: WHITE-MATTER TRACTS, INTEGRATED FUNCTIONAL NEURONAVIGATION, MAGNETIC-RESONANCE TRACTOGRAPHY, CEREBRAL-ARTERY INFARCTION, MULTIPLE-SCLEROSIS BRAIN, TEMPORAL-LOBE EPILEPSY, DTI FIBER TRACKING, TENSOR TRACTOGRAPHY, SPINAL-CORD, PYRAMIDAL TRACT
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neuroinflammation
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health > ICH Developmental Neurosciences Prog
URI: http://discovery.ucl.ac.uk/id/eprint/152819
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