UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Optimal cue combination and landmark-stability learning in the head direction system.

Jeffery, KJ; Page, HJ; Stringer, SM; (2016) Optimal cue combination and landmark-stability learning in the head direction system. The Journal of Physiology , 594 (22) pp. 6527-6534. 10.1113/JP272945. Green open access

[img]
Preview
Text
Jeffery_Jeffery et al (for OA deposit).pdf

Download (770kB) | Preview

Abstract

Maintaining a sense of direction requires combining information from static environmental landmarks with dynamic information about self-motion. This is accomplished by the head direction system, whose neurons - head direction cells - encode specific head directions. When the brain integrates information in sensory domains, this process is almost always 'optimal' - that is, inputs are weighted according to their reliability. Evidence suggests cue combination by head direction cells may also be optimal. The simplicity of the head direction signal, together with the detailed knowledge we have about the anatomy and physiology of the underlying circuit, therefore makes this system a tractable model with which to discover how optimal cue combination occurs at a neural level. In the head direction system, cue interactions are thought to occur on an attractor network of interacting head direction neurons, but attractor dynamics predict a winner-take-all decision between cues, rather than optimal combination. However, optimal cue combination in an attractor could be achieved via plasticity in the feedforward connections from external sensory cues (i.e. the landmarks) onto the ring attractor. Short-term plasticity would allow rapid re-weighting that adjusts the final state of the network in accordance with cue reliability (reflected in the connection strengths), while longer term plasticity would allow long-term learning about this reliability. Although these principles were derived to model the head direction system, they could potentially serve to explain optimal cue combination in other sensory systems more generally.

Type: Article
Title: Optimal cue combination and landmark-stability learning in the head direction system.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1113/JP272945
Publisher version: http://dx.doi.org/10.1113/JP272945
Additional information: © 2016 The Authors. The Journal of Physiology. © 2016 The Physiological Society. This is the peer reviewed version of the following article: Jeffery, K. J., Page, H. J. I. and Stringer, S. M. (2016), Optimal cue combination and landmark-stability learning in the head direction system. J Physiol, 594: 6527–6534., which has been published in final form at http://dx.doi.org/10.1113/JP272945. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Keywords: Attractor networks, cue combination, sensory integration
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Experimental Psychology
URI: http://discovery.ucl.ac.uk/id/eprint/1522137
Downloads since deposit
58Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item