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Melilotoside Derivatives from Artemisia splendens (Asteraceae)

Afshar, FH; Delazar, A; Nazemiyeh, H; Nahar, L; Moghaddam, SB; Mbaebie, BO; Gibbons, S; (2017) Melilotoside Derivatives from Artemisia splendens (Asteraceae). Records of Natural Products , 11 (1) pp. 43-50. Green open access

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Abstract

A combination of solid-phase-extraction (SPE) and reversed-phase preparative high-performance liquid chromatography (prep-HPLC) of the methanolic extract of the aerial parts of Artemisia splendens (common name: “Asia Minor Wormwood”), an endemic Iranian species, afforded Z- and E-melilotosides (1 and 2), Z- and E-4-methoxy-melilotosides (3 and 4), and a new dimer, bis-ortho-Z-melilotoside (5, named: splendenoside). Whilst the structures of these compounds (1-5) were elucidated unequivocally by spectroscopic means, the in vitro free-radical-scavenging property of 1-5 was determined by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. This is the first report on the occurrence of any melilotoside derivatives in the genus Artemisia.

Type: Article
Title: Melilotoside Derivatives from Artemisia splendens (Asteraceae)
Open access status: An open access version is available from UCL Discovery
Publisher version: http://www.acgpubs.org/RNP/2017/Volume11/Abstracts...
Language: English
Additional information: Copyright © 2016 ACG Publications. All rights reserved.
Keywords: rtemisia splendens; Asteraceae; 2,2-diphenyl-1-picrylhydrazyl (DPPH); free-radical scavenger; melilotoside; splendenoside
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > SoP Pharmaceutical and Bio Chemistry
URI: http://discovery.ucl.ac.uk/id/eprint/1521953
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