MILLER, DH and BARKHOF, F and BERRY, I and KAPPOS, L and SCOTTI, G and THOMPSON, AJ (1991) MAGNETIC-RESONANCE-IMAGING IN MONITORING THE TREATMENT OF MULTIPLE-SCLEROSIS - CONCERTED ACTION GUIDELINES. J NEUROL NEUROSUR PS , 54 (8) 683 - 688.
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Serial gadolinium enhanced MRI of the brain detects much clinically silent disease activity in early relapsing-remitting and secondary progressive multiple sclerosis (MS), and thus has an important role in monitoring the effects of therapy. Based on the proceedings of a recent Commission of the European Communities (CEC) workshop and a review of the literature, guidelines are presented for using MRI to monitor treatment trials in MS. The guidelines consider: A) MRI system and techniques; B) patient selection; C) trial design; D) analysis of results. Priorities for future research are also indicated.
|Title:||MAGNETIC-RESONANCE-IMAGING IN MONITORING THE TREATMENT OF MULTIPLE-SCLEROSIS - CONCERTED ACTION GUIDELINES|
|Keywords:||CEREBRAL WHITE MATTER, STATUS SCALE EDSS, GADOLINIUM-DTPA, RELAPSING PATIENTS, SERIAL, BRAIN, MRI, LESIONS, DISEASE, ENCEPHALOMYELITIS|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > IoN - Neuroinflammation|
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