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Antibody-targeted nanoparticles for cancer treatment

Carter, T; Mulholland, P; Chester, K; (2016) Antibody-targeted nanoparticles for cancer treatment. Immunotherapy , 8 (8) pp. 941-958. 10.2217/imt.16.11. Green open access

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Abstract

Nanoparticles (NPs) are diverse and versatile with physical properties that can be employed for use in cancer medicine. Targeting NPs using antibodies and antibody fragments could overcome some of the limitations seen with current targeted therapies. This review will discuss the role of antibody-targeted NPs in the treatment of cancer: as delivery vehicles, targeted theranostic agents and in the evolving field of cancer hyperthermia.

Type: Article
Title: Antibody-targeted nanoparticles for cancer treatment
Open access status: An open access version is available from UCL Discovery
DOI: 10.2217/imt.16.11
Publisher version: http://dx.doi.org/10.2217/imt.16.11
Language: English
Additional information: Copyright © 2016 Future Medicine Ltd.
Keywords: Science & Technology, Life Sciences & Biomedicine, Immunology, Antibodies, Cancer Treatment, Clinical Translation, Hyperthermia, Nanoparticles, Targeting, Theranostics, Drug-Delivery Systems, Single-Chain Antibody, Iron-Oxide Nanoparticles, Walled Carbon Nanotubes, Advanced Solid Tumors, Stem-Like Cells, Gold Nanoparticles, Monoclonal-Antibody, Magnetic Nanoparticles, Breast-Cancer
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology
URI: http://discovery.ucl.ac.uk/id/eprint/1504584
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