Kang, J and Richardson, JP and Macmillan, D (2009) 3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters. CHEM COMMUN (4) 407 - 409. 10.1039/b815888f.
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Abstract
Peptides and proteins fragment sequence-specifically in the presence of 3-mercaptopropionic acid to afford thioesters which can be used in native chemical ligation reactions.
| Type: | Article |
|---|---|
| Title: | 3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters |
| DOI: | 10.1039/b815888f |
| Keywords: | NATIVE CHEMICAL LIGATION, SOLID-PHASE SYNTHESIS, C-TERMINAL THIOESTERS, FMOC-BASED SYNTHESIS, ALPHA-THIOESTERS, THIOESTERIFICATION, GENERATION, STRATEGIES, FACILE, SHIFT |
| UCL classification: | UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Chemistry |
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