UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Update on the management of Duchenne muscular dystrophy

Manzur, AY; Kinali, M; Muntoni, F; (2008) Update on the management of Duchenne muscular dystrophy. ARCH DIS CHILD , 93 (11) 986 - 990. 10.1136/adc.2007.118141.

Full text not available from this repository.

Abstract

Duchenne muscular dystrophy (DMD) is familiar to paediatricians as the most common childhood muscular dystrophy and leads to severe disability and early death in the late teenage years if untreated. Improvements in general care, glucocorticoid corticosteroid treatment, non-invasive ventilatory support, and cardiomyopathy and scoliosis management have significantly changed the course of DMD in treated individuals, so that survival into adulthood is now a realistic possibility for most patients. This has important implications for the medical and social sectors involved in the transition to adult medical services and the provision of suitable employment and social care. Multidisciplinary team working for optimal management of DMD-specific multisystem complications is essential, and collaboration in disease specific national clinical networks is recommended. Several curative therapeutic strategies including cell and gene therapy are being pursued but are still at an experimental stage.

Type: Article
Title: Update on the management of Duchenne muscular dystrophy
DOI: 10.1136/adc.2007.118141
Keywords: RANDOMIZED CONTROLLED-TRIAL, HOME NOCTURNAL VENTILATION, CORTICOSTEROID TREATMENT, MUSCLE BIOPSY, MUTATIONS, SURVIVAL, DISEASE, GENE, AMPLIFICATION, PERINDOPRIL
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health > ICH Developmental Neurosciences Prog
URI: http://discovery.ucl.ac.uk/id/eprint/150164
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item