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CATH-Gene3D: Generation of the Resource and Its Use in Obtaining Structural and Functional Annotations for Protein Sequences.

Dawson, NL; Sillitoe, I; Lees, JG; Lam, SD; Orengo, CA; (2017) CATH-Gene3D: Generation of the Resource and Its Use in Obtaining Structural and Functional Annotations for Protein Sequences. In: UNSPECIFIED (pp. 79-110).

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Abstract

This chapter describes the generation of the data in the CATH-Gene3D online resource and how it can be used to study protein domains and their evolutionary relationships. Methods will be presented for: comparing protein structures, recognizing homologs, predicting domain structures within protein sequences, and subclassifying superfamilies into functionally pure families, together with a guide on using the webpages.

Type: Book chapter
Title: CATH-Gene3D: Generation of the Resource and Its Use in Obtaining Structural and Functional Annotations for Protein Sequences.
DOI: 10.1007/978-1-4939-6783-4_4
Keywords: Annotation, Classification, Database, Function prediction, Protein domain, Sequence, Structural model prediction, Structure, Algorithms, Computational Biology, Databases, Genetic, Models, Molecular, Molecular Sequence Annotation, Protein Binding, Protein Conformation, Protein Interaction Domains and Motifs, Proteins, Software, Structure-Activity Relationship, Web Browser, Workflow
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1499004
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