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The integration and interpretation of pharmacogenomics. A comparative study between the United States of America and Europe: towards better health care

Bartlett, MJ; Shephard, EA; (2016) The integration and interpretation of pharmacogenomics. A comparative study between the United States of America and Europe: towards better health care. Drug Metabolism and Personalized Therapy , 31 (2) pp. 91-96. 10.1515/dmpt-2015-0044. Green open access

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Abstract

The study of pharmacogenomics has, by harnessing sequence information from human genomes, the potential to lead to novel approaches in drug discovery, an individualized application of drug therapy, and new insights into disease prevention. For this potential to be realized results need to be interpreted to the prescriber into a format which dictates an action. This mini review briefly describes the history, the regulatory environment, opinions towards, and implementation, integration and interpretation of pharmacogenomics in the United States of America and Europe. The article discusses also how interpretation of pharmacogenomics could move forward to better implementation in health care.

Type: Article
Title: The integration and interpretation of pharmacogenomics. A comparative study between the United States of America and Europe: towards better health care
Open access status: An open access version is available from UCL Discovery
DOI: 10.1515/dmpt-2015-0044
Publisher version: http://dx.doi.org/10.1515/dmpt-2015-0044
Language: English
Additional information: Copyright © 2016 Walter de Gruyter GmbH. This is the version of record published in Drug Metabolism and Personalized Therapy (DOI: 10.1515/dmpt-2015-0044) and available at http://www.degruyter.com/view/j/dmdi.2016.31.issue-2/dmpt-2015-0044/dmpt-2015-0044.xml
Keywords: implementation; pharmacogenetics; pharmacogenomics; regulatory bodies
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1494863
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