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Is regeneration in Drosophila the result of epimorphic regulation?

Dale, L; Bownes, M; (1980) Is regeneration in Drosophila the result of epimorphic regulation? Wilhelm Roux's Archives of Developmental Biology , 189 (2) pp. 91-96. 10.1007/BF00848497.

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Abstract

It has been known for many years that when a wing disc of Drosophila is bisected, and the fragments cultured in adult females, regulation occurs and either a complete disc is regenerated or the fragment is duplicated. We have investigated how this regeneration process occurs. To establish which cells contribute to the regenerate, and thus determine if regeneration is the result of epimorphic regulation, fragments of discs, after culture in an adult for one to five days, were exposed to3H-thymidine to label replicating cells. Imaginal discs, both whole and as regenerating fragments, undergo some DNA replication which is distributed throughout the disc, but cut discs frequently show clusters of labelled cells around the wound, indicating that regeneration is probably epimorphic. © 1980 Springer-Verlag.

Type: Article
Title: Is regeneration in Drosophila the result of epimorphic regulation?
DOI: 10.1007/BF00848497
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1493762
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