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Neuronal Inhibition under the Spotlight

Mortensen, M; Smart, TG; (2015) Neuronal Inhibition under the Spotlight. Neuron , 88 (5) pp. 845-847. 10.1016/j.neuron.2015.11.014. Green open access

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Abstract

In this issue of Neuron, Lin et al. (2015) report an optical method to precisely manipulate the activity of GABAA receptors by designing a mutant receptor that binds photosensitive compounds. This allows for studying GABAA receptors in situ and represents a valuable tool to investigate how inhibition affects brain physiology.

Type: Article
Title: Neuronal Inhibition under the Spotlight
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.neuron.2015.11.014
Publisher version: http://dx.doi.org/10.1016/j.neuron.2015.11.014
Language: English
Additional information: Copyright © 2015. This manuscript version is published under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International licence (CC BY-NC-ND 4.0). This licence allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licences are available at http://creativecommons.org/licenses/by/4.0.
Keywords: Animals, Brain, Humans, Neural Inhibition, Optogenetics, Receptors, GABA-A, Synaptic Transmission
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology
URI: https://discovery.ucl.ac.uk/id/eprint/1483365
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