UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

The Drosophila photoreceptor as a model system for studying signalling at membrane contact sites

Yadav, S; Cockcroft, S; Raghu, P; (2016) The Drosophila photoreceptor as a model system for studying signalling at membrane contact sites. Biochemical Society Transactions , 44 (2) pp. 447-451. 10.1042/BST20150256. Green open access

[img]
Preview
Text
Cockcroft_Yadav et.al_2015_v6.0.pdf

Download (2MB) | Preview

Abstract

Several recent studies have demonstrated the existence of membrane contact sites (MCS) between intracellular organelles in eukaryotic cells. Recent exciting studies have also demonstrated the existence of biomolecular interactions at these contact sites in mediating changes in the membrane composition of the cellular compartments. However, the role of such contact sites in regulating organelle function and physiological processes remains less clear. In this review we discuss the existence of a contact site between the plasma membrane (PM) and the endoplasmic reticulum (ER) inDrosophilaphotoreceptors. Further, we discuss the role of specific proteins present at this location in regulating phospholipid turnover and its impact in regulating a physiological process, namely phototransduction.

Type: Article
Title: The Drosophila photoreceptor as a model system for studying signalling at membrane contact sites
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1042/BST20150256
Publisher version: http://doi.org/10.1042/BST20150256
Language: English
Additional information: © 2016 Authors; published by Portland Press Limited
Keywords: 5)P2] turnover, 5-bisphosphate [PI(4, Drosophila, RDGB, lipid transfer proteins, membrane contact sites, micovillar photoreceptors, phosphatidylinositol 4 Micovillar photoreceptors, membrane contact sites, PI(4,5)P2 turnover, lipid transfer proteins, RDGB, Drosophila
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology
URI: http://discovery.ucl.ac.uk/id/eprint/1482952
Downloads since deposit
106Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item