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Bioinformatics tools and database resources for systems genetics analysis in mice--a short review and an evaluation of future needs.

Durrant, C; Swertz, MA; Alberts, R; Arends, D; Möller, S; Mott, R; Prins, P; ... Schughart, K; + view all (2012) Bioinformatics tools and database resources for systems genetics analysis in mice--a short review and an evaluation of future needs. Brief Bioinform , 13 (2) pp. 135-142. 10.1093/bib/bbr026.

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Abstract

During a meeting of the SYSGENET working group 'Bioinformatics', currently available software tools and databases for systems genetics in mice were reviewed and the needs for future developments discussed. The group evaluated interoperability and performed initial feasibility studies. To aid future compatibility of software and exchange of already developed software modules, a strong recommendation was made by the group to integrate HAPPY and R/qtl analysis toolboxes, GeneNetwork and XGAP database platforms, and TIQS and xQTL processing platforms. R should be used as the principal computer language for QTL data analysis in all platforms and a 'cloud' should be used for software dissemination to the community. Furthermore, the working group recommended that all data models and software source code should be made visible in public repositories to allow a coordinated effort on the use of common data structures and file formats.

Type: Article
Title: Bioinformatics tools and database resources for systems genetics analysis in mice--a short review and an evaluation of future needs.
Location: England
DOI: 10.1093/bib/bbr026
Keywords: Algorithms, Animals, Computational Biology, Databases, Factual, Gene Regulatory Networks, Mice, Quantitative Trait Loci, Software
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
URI: http://discovery.ucl.ac.uk/id/eprint/1479796
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