McKelvey, A;
Pateman, K;
Balchin, I;
Peebles, DM;
Rodeck, CH;
David, AL;
(2017)
Total uterine artery blood volume flow rate in nulliparous women (TVFR) is associated with birthweight and gestation at delivery.
Ultrasound in Obstetrics and Gynecology
, 49
(1)
pp. 54-60.
10.1002/uog.15917.
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Abstract
OBJECTIVES: To investigate the relationship between total uterine artery blood volume flow rate (TVFR) and birthweight and gestation at delivery and to establish normal ranges of TVFR through pregnancy. METHODS: A prospective cohort study at University College London Hospital, in which 334 nulliparous women booking for antenatal care had measurement of TVFR by transabdominal ultrasound at 12, 20 and 24 weeks. RESULTS: 551 scans were performed. There was a significant and positive correlation between total uterine blood volume flow at 11-13 weeks (TVFR1) and 22-26 weeks (TVFR2) and birthweight. For every 100 unit increase in TVFR1 and TVFR2, there was a 45 g and 27 g increase in birthweight respectively. There was also a positive association between TVFR1 and gestation at delivery, with a 1.4 day increase in gestation for every 100 unit increase of TVFR1. CONCLUSION: Ultrasound measurement of TVFR in the first trimester is significantly associated with both birth weight and gestation at delivery.
| Type: | Article |
|---|---|
| Title: | Total uterine artery blood volume flow rate in nulliparous women (TVFR) is associated with birthweight and gestation at delivery |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/uog.15917 |
| Publisher version: | http://dx.doi.org/10.1002/uog.15917 |
| Language: | English |
| Additional information: | This is the peer reviewed version of the following article: McKelvey, A; Pateman, K; Balchin, I; Peebles, DM; Rodeck, CH; David, AL; (2017) Total uterine artery blood volume flow rate in nulliparous women (TVFR) is associated with birthweight and gestation at delivery. Ultrasound in Obstetrics & Gynecology , 49 (1) pp. 54-60, which has been published in final form at http://dx.doi.org/10.1002/uog.15917. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Access may initially be restricted by the publisher. |
| Keywords: | Birthweight, Bloodflow, Doppler, Gestation, Rate, Ultrasound, Uterine |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health > Maternal and Fetal Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1477071 |
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