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Patterns of selective involvement of thigh muscles in neuromuscular disease.

Schwartz, MS; Swash, M; Ingram, DA; Davis, GR; Thompson, AJ; Thakkar, C; Hart, G; (1988) Patterns of selective involvement of thigh muscles in neuromuscular disease. Muscle Nerve , 11 (12) 1240 - 1245. 10.1002/mus.880111208.

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Abstract

In 14 patients with limb girdle muscular dystrophy, polymyositis, and type 3 spinal muscular atrophy, CT scans of the thigh muscles were correlated with single fiber EMG studies in vastus lateralis, semimembranosus and biceps femoris muscles. There was a relation between the extent of CT scan abnormality and increased fiber density in the three muscles studied, except in the most severely affected muscles in which in some muscles the fiber density values were lower than expected. These results were independent of the underlying pathology. Correlative CT/SFEMG studies provide insights into the pattern of selective involvement of certain muscles in neuromuscular disorders.

Type: Article
Title: Patterns of selective involvement of thigh muscles in neuromuscular disease.
Location: UNITED STATES
DOI: 10.1002/mus.880111208
Language: English
Keywords: Adult, Female, Humans, Male, Middle Aged, Muscles, Neuromuscular Diseases, Thigh, Tomography, X-Ray Computed
UCL classification: UCL > School of Life and Medical Sciences > Faculty of Brain Sciences
URI: http://discovery.ucl.ac.uk/id/eprint/147299
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