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Accuracy and Test-Retest Reproducibility of Two-Dimensional Knowledge-Based Volumetric Reconstruction of the Right Ventricle in Pulmonary Hypertension

Knight, DS; Schwaiger, JP; Krupickova, S; Davar, J; Muthurangu, V; Coghlan, JG; (2015) Accuracy and Test-Retest Reproducibility of Two-Dimensional Knowledge-Based Volumetric Reconstruction of the Right Ventricle in Pulmonary Hypertension. Journal of the American Society of Echocardiography , 28 (8) pp. 989-998. 10.1016/j.echo.2015.02.020. Green open access

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Abstract

Right heart function is the key determinant of symptoms and prognosis in pulmonary hypertension (PH), but the right ventricle has a complex geometry that is challenging to quantify by two-dimensional (2D) echocardiography. A novel 2D echocardiographic technique for right ventricular (RV) quantitation involves knowledge-based reconstruction (KBR), a hybrid of 2D echocardiography-acquired coordinates localized in three-dimensional space and connected by reference to a disease-specific RV shape library. The aim of this study was to determine the accuracy of 2D KBR against cardiac magnetic resonance imaging in PH and the test-retest reproducibility of both conventional 2D echocardiographic RV fractional area change (FAC) and 2D KBR.

Type: Article
Title: Accuracy and Test-Retest Reproducibility of Two-Dimensional Knowledge-Based Volumetric Reconstruction of the Right Ventricle in Pulmonary Hypertension
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.echo.2015.02.020
Publisher version: http://dx.doi.org/10.1016/j.echo.2015.02.020
Language: English
Additional information: Copyright 2015 by the American Society of Echocardiography. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keywords: Magnetic resonance imaging, Pulmonary hypertension, Reproducibility of results, Right ventricular function, Transthoracic echocardiography
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science > Children's Cardiovascular Disease
URI: http://discovery.ucl.ac.uk/id/eprint/1472613
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