Anderson, JC;
Rundell, CD;
(2016)
Stereoselective Synthesis of Densely Substituted Tetrahydroquinolines by a Conjugate Addition Nitro-Mannich Reaction with Carbon Nucleophiles.
Synlett
, 27
(1)
pp. 41-44.
10.1055/s-0035-1560815.
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Abstract
Conjugate addition of an alkyl group to a series of 2-imino-nitrostyrenes and then addition of trifluoroacetic acid initiates a nitro-Mannich cyclisation to give cis,cis-2,3,4-substituted tetrahydroquinolines in good yield and high diastereoselectivity.
| Type: | Article |
|---|---|
| Title: | Stereoselective Synthesis of Densely Substituted Tetrahydroquinolines by a Conjugate Addition Nitro-Mannich Reaction with Carbon Nucleophiles |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1055/s-0035-1560815 |
| Publisher version: | http://dx.doi.org/10.1055/s-0035-1560815 |
| Language: | English |
| Additional information: | © Georg Thieme Verlag Stuttgart · New York |
| Keywords: | amines, stereoselective synthesis, cyclisation, imines, quinolines |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1472076 |
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