Gibson, SM;
Lanigan, RM;
Benhamou, L;
Aliev, AE;
Sheppard, TD;
(2015)
A lactate-derived chiral aldehyde for determining the enantiopurity of enantioenriched primary amines.
Organic & Biomolecular Chemistry
, 13
(34)
pp. 9050-9054.
10.1039/c5ob01398d.
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Abstract
In this paper we describe the use of a chiral aldehyde derived from lactate esters for determining the enantiopurity of primary amines, via the formation of diastereomeric imines. The method was shown to be suitable for reproducibly determining the enantiopurity of a diverse set of chiral amines. Both enantiomers of the aldehyde can be prepared in two steps from commercially available materials.
| Type: | Article |
|---|---|
| Title: | A lactate-derived chiral aldehyde for determining the enantiopurity of enantioenriched primary amines |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1039/c5ob01398d |
| Publisher version: | http://dx.doi.org/10.1039/c5ob01398d |
| Additional information: | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1471701 |
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