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Intervening in ageing to prevent the diseases of ageing

Partridge, L; (2014) Intervening in ageing to prevent the diseases of ageing. Trends in Endocrinology & Metabolism , 25 (11) pp. 555-557. 10.1016/j.tem.2014.08.003. Green open access

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Abstract

Increases in human lifespan worldwide have revealed that advancing age is the predominant risk factor for major life-threatening diseases. Recent work has shown that ageing in diverse animals, including humans, is malleable to specific types of genetic mutation, diet, and drugs that can extend lifespan and improve health during ageing. These findings point to the prospect of broad-spectrum preventive medicine for the diseases of ageing based on intervention in relevant aspects of the ageing process itself.

Type: Article
Title: Intervening in ageing to prevent the diseases of ageing
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.tem.2014.08.003
Publisher version: http://dx.doi.org/10.1016/j.tem.2014.08.003
Language: English
Additional information: 2014 The Authors.Published by Elsevier Ltd. This is an open access article under the CC BY license(http://creativecommons.org/licenses/by/3.0/). http://dx.doi.org/10.1016/j.tem.2014.08.003
Keywords: Ageing; ageing-related disease; insulin/insulin-like growth factor and TOR signalling
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
URI: https://discovery.ucl.ac.uk/id/eprint/1470525
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