Al-Hamad, A;
Porter, S;
Fedele, S;
(2015)
Orofacial Granulomatosis.
Dermatologic Clinics
, 33
(3)
pp. 433-446.
10.1016/j.det.2015.03.008.
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Abstract
Orofacial granulomatosis (OFG) is an uncommon chronic inflammatory disorder of the orofacial region. It is characterized by subepithelial noncaseating granulomas and has a spectrum of possible clinical manifestations ranging from subtle oral mucosal swelling to permanent disfiguring fibrous swelling of the lips and face. Etiopathogenesis is unknown. A range of systemic granulomatous disorders, including Crohn disease and sarcoidosis, may cause orofacial manifestations that cannot be distinguished from those of OFG. Treatment of OFG has proven difficult and unsatisfactory, with no single therapeutic model showing consistent efficacy in reducing orofacial swelling and mucosal inflammation.
| Type: | Article |
|---|---|
| Title: | Orofacial Granulomatosis |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.det.2015.03.008 |
| Publisher version: | http://dx.doi.org/10.1016/j.det.2015.03.008 |
| Language: | English |
| Keywords: | Crohn's disease, Granulomas, Granulomatous cheilitis, Melkersson-Rosenthal syndrome, Orofacial granulomatosis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1470143 |
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