Haque, T;
Rahman, KM;
Thurston, DE;
Hadgraft, J;
Lane, ME;
(2015)
Topical therapies for skin cancer and actinic keratosis.
European Journal of Pharmaceutical Sciences
, 77
pp. 279-289.
10.1016/j.ejps.2015.06.013.
Preview |
Text
EJPS-D-15-00385R1 (1).pdf Download (640kB) | Preview |
Abstract
The global incidence of skin cancer and actinic keratosis (AK) has increased dramatically in recent years. Although many tumours are treated with surgery or radiotherapy topical therapy has a place in the management of certain superficial skin neoplasms and AK. This review considers skin physiology, non-melanoma skin cancer (NMSC), the relationship between AK and skin cancer and drugs administered topically for these conditions. The dermal preparations for management of NMSC and AK are discussed in detail. Notably few studies have examined drug disposition in cancerous skin or in AK. Finally, recent novel approaches for targeting of drugs to skin neoplasms and AK are discussed.
| Type: | Article |
|---|---|
| Title: | Topical therapies for skin cancer and actinic keratosis. |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.ejps.2015.06.013 |
| Publisher version: | http://dx.doi.org/10.1016/j.ejps.2015.06.013 |
| Language: | English |
| Additional information: | Author's preprint version. This article is made available under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International license (CC BY-NC-ND 4.0). This license allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licenses are available at http://creativecommons.org/ licenses/by/4.0 |
| Keywords: | Actinic keratosis, Cancer, Formulation, Melanoma, Skin, Topical |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1470025 |
Archive Staff Only
 |
View Item |
