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Microstructural parameter estimation in vivo using diffusion MRI and structured prior information.

Clayden, JD; Nagy, Z; Weiskopf, N; Alexander, DC; Clark, CA; (2016) Microstructural parameter estimation in vivo using diffusion MRI and structured prior information. Magnetic Resonance in Medicine , 75 (4) pp. 1787-1796. 10.1002/mrm.25723. Green open access

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Abstract

Diffusion MRI has recently been used with detailed models to probe tissue microstructure. Much of this work has been performed ex vivo with powerful scanner hardware, to gain sensitivity to parameters such as axon radius. By contrast, performing microstructure imaging on clinical scanners is extremely challenging.

Type: Article
Title: Microstructural parameter estimation in vivo using diffusion MRI and structured prior information.
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/mrm.25723
Publisher version: http://dx.doi.org/10.1002/mrm.25723
Language: English
Additional information: © 2015 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: Bayesian, MCMC, Dual spin-echo, Microstructure, Prior, Twice-refocused spin-echo
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Department of Neuromuscular Diseases
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health > ICH Developmental Neurosciences Prog
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
URI: http://discovery.ucl.ac.uk/id/eprint/1469320
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