Fibroblast biology. Development and differentiation of synovial fibroblasts in arthritis.
Synovial fibroblasts occur as two phenotypes--intimal and subintimal. The specialised intimal phenotype includes expression of uridine diphosphoglucose dehydrogenase (UDPGD), vascular cell adhesion molecule-1 (VCAM-1) and complement decay-accelerating factor (DAF). These gene products contribute to specialised functions relating to tissue movement and leucocyte traffic.
|Title:||Fibroblast biology. Development and differentiation of synovial fibroblasts in arthritis.|
|Keywords:||Animals, Arthritis, Cell Differentiation, Fibroblasts, Humans, Synovial Membrane|
|UCL classification:||UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences
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