Escott-Price, V;
International, Parkinson's Disease Genomics Consortium;
Nalls, MA;
Morris, HR;
Lubbe, S;
Brice, A;
Gasser, T;
... IPDGC, consortium members; + view all
(2015)
Polygenic risk of Parkinson disease is correlated with disease age at onset.
Annals of Neurology
, 77
(4)
pp. 582-591.
10.1002/ana.24335.
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Abstract
We have investigated the polygenic architecture of Parkinson disease (PD) and have also explored the potential relationship between an individual's polygenic risk score and their disease age at onset.
| Type: | Article |
|---|---|
| Title: | Polygenic risk of Parkinson disease is correlated with disease age at onset |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/ana.24335 |
| Publisher version: | http://dx.doi.org/10.1002/ana.24335 |
| Language: | English |
| Additional information: | ©2015 The Authors Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited |
| Keywords: | Age of Onset, Aged, Aged, 80 and over, Female, Genetic Predisposition to Disease, Humans, Male, Middle Aged, Multifactorial Inheritance, Parkinson Disease, Polymorphism, Single Nucleotide, Retrospective Studies, Risk Factors |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1465039 |
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