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Synchrotron based planar imaging and digital tomosynthesis of breast and biopsy phantoms using a CMOS active pixel sensor

Szafraniec, MB; Konstantinidis, AC; Tromba, G; Dreossi, D; Vecchio, S; Rigon, L; Sodini, N; ... Olivo, A; + view all (2015) Synchrotron based planar imaging and digital tomosynthesis of breast and biopsy phantoms using a CMOS active pixel sensor. Physica Medica , 31 (2) 192 - 198. 10.1016/j.ejmp.2014.11.003. Green open access

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Abstract

The SYRMEP (SYnchrotron Radiation for MEdical Physics) beamline at Elettra is performing the first mammography study on human patients using free-space propagation phase contrast imaging. The stricter spatial resolution requirements of this method currently force the use of conventional films or specialized computed radiography (CR) systems. This also prevents the implementation of three-dimensional (3D) approaches. This paper explores the use of an X-ray detector based on complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) technology as a possible alternative, for acquisitions both in planar and tomosynthesis geometry.Results indicate higher quality of the images acquired with the synchrotron set-up in both geometries. This improvement can be partly ascribed to the use of parallel, collimated and monochromatic synchrotron radiation (resulting in scatter rejection, no penumbra-induced blurring and optimized X-ray energy), and partly to phase contrast effects. Even though the pixel size of the used detector is still too large - and thus suboptimal - for free-space propagation phase contrast imaging, a degree of phase-induced edge enhancement can clearly be observed in the images.

Type: Article
Title: Synchrotron based planar imaging and digital tomosynthesis of breast and biopsy phantoms using a CMOS active pixel sensor
Location: Amsterdam
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ejmp.2014.11.003
Publisher version: http://www.sciencedirect.com/science/journal/11201...
Language: English
Additional information: Copyright © 2014 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
Keywords: 3D breast imaging, APS, CMOS, Edge enhancement, Flat panel detector, Image contrast, Phase contrast imaging, Tomosynthesis
UCL classification: UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1461714
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