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Cardiac magnetic resonance imaging in patients with systemic lupus erythematosus

O'Neill, SG; Woldman, S; Bailliard, F; Norman, W; McEwan, J; Isenberg, DA; ... Rahman, A; + view all (2009) Cardiac magnetic resonance imaging in patients with systemic lupus erythematosus. ANN RHEUM DIS , 68 (9) 1478 - 1481. 10.1136/ard.2008.098053.

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Abstract

Objectives: To delineate the cardiac magnetic resonance (MR) appearances of cardiovascular disease (CVD) in patients with systemic lupus erythematosus (SLE), in comparison with transthoracic echocardiographs.Methods: Cardiac MR was performed on 22 patients with SLE-11 with previous CVD and 11 matched controls-using late gadolinium contrast enhancement (LGE) to identify areas of myocardial scarring; Transthoracic echocardiography (TTE) was performed on the same day.Results: Twenty female and two male patients participated. LGE was seen in 5/11 subjects in the CVD group (4/5 with previous myocardial infarction) and 1/11 in the control group. TTE detected myocardial abnormalities in 2/6 patients with LGE.Conclusion: The cardiac MR appearance of CVD in these patients with SLE was suggestive of coronary disease, rather than cumulative inflammatory muscle damage. Cardiac MR detected more abnormalities than TTE. Further studies of cardiac MR in patients with SLE are warranted to investigate these preliminary findings.

Type:Article
Title:Cardiac magnetic resonance imaging in patients with systemic lupus erythematosus
DOI:10.1136/ard.2008.098053
Keywords:DISEASE, ATHEROSCLEROSIS, WOMEN, CLASSIFICATION, CRITERIA, COHORT, HEART, AGE
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of) > Inflammation
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of) > Metabolism and Experimental Therapeutics
UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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