O'Neill, SG and Woldman, S and Bailliard, F and Norman, W and McEwan, J and Isenberg, DA and Taylor, AM and Rahman, A (2009) Cardiac magnetic resonance imaging in patients with systemic lupus erythematosus. ANN RHEUM DIS , 68 (9) 1478 - 1481. 10.1136/ard.2008.098053.
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Objectives: To delineate the cardiac magnetic resonance (MR) appearances of cardiovascular disease (CVD) in patients with systemic lupus erythematosus (SLE), in comparison with transthoracic echocardiographs.Methods: Cardiac MR was performed on 22 patients with SLE-11 with previous CVD and 11 matched controls-using late gadolinium contrast enhancement (LGE) to identify areas of myocardial scarring; Transthoracic echocardiography (TTE) was performed on the same day.Results: Twenty female and two male patients participated. LGE was seen in 5/11 subjects in the CVD group (4/5 with previous myocardial infarction) and 1/11 in the control group. TTE detected myocardial abnormalities in 2/6 patients with LGE.Conclusion: The cardiac MR appearance of CVD in these patients with SLE was suggestive of coronary disease, rather than cumulative inflammatory muscle damage. Cardiac MR detected more abnormalities than TTE. Further studies of cardiac MR in patients with SLE are warranted to investigate these preliminary findings.
|Title:||Cardiac magnetic resonance imaging in patients with systemic lupus erythematosus|
|Keywords:||DISEASE, ATHEROSCLEROSIS, WOMEN, CLASSIFICATION, CRITERIA, COHORT, HEART, AGE|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of) > Cardiovascular Medicine|
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of) > Inflammation
UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
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