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KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia

Etchin, J; Sanda, T; Mansour, MR; Kentsis, A; Montero, J; Le, BT; Christie, AL; ... Look, AT; + view all (2013) KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia. BRITISH JOURNAL OF HAEMATOLOGY , 161 (1) pp. 117-127. 10.1111/bjh.12231.

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Type: Article
Title: KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia
DOI: 10.1111/bjh.12231
Keywords: Science & Technology, Life Sciences & Biomedicine, Hematology, Acute leukaemia, all, aml, new drugs for leukaemia, new drugs for lymphoma, NUCLEOCYTOPLASMIC TRANSPORT, IN-VIVO, CANCER, EXPRESSION, SIGNALS, RESTORATION, RESISTANCE, MUTATIONS, PROGNOSIS, PROTEINS
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology
URI: http://discovery.ucl.ac.uk/id/eprint/1456265
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