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CATH: comprehensive structural and functional annotations for genome sequences

Sillitoe, I; Lewis, TE; Cuff, A; Das, S; Ashford, P; Dawson, NL; Furnham, N; ... Orengo, CA; + view all (2014) CATH: comprehensive structural and functional annotations for genome sequences. Nucleic Acids Research , 43 (D1) D376-D381. 10.1093/nar/gku947. Green open access

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Abstract

The latest version of the CATH-Gene3D protein structure classification database (4.0, http://www.cathdb.info) provides annotations for over 235 000 protein domain structures and includes 25 million domain predictions. This article provides an update on the major developments in the 2 years since the last publication in this journal including: significant improvements to the predictive power of our functional families (FunFams); the release of our 'current' putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (CATH-40) and a number of improvements to the web pages.

Type: Article
Title: CATH: comprehensive structural and functional annotations for genome sequences
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/nar/gku947
Publisher version: http://dx.doi.org/10.1093/nar/gku947
Language: English
Additional information: © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/1453283
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