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Prospective cohort study of the effectiveness of smoking cessation treatments used in the "real world".

Kotz, D; Brown, J; West, R; (2014) Prospective cohort study of the effectiveness of smoking cessation treatments used in the "real world". Mayo Clin Proc , 89 (10) 1360 - 1367. 10.1016/j.mayocp.2014.07.004. Green open access

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Abstract

Objective To estimate the “real-world” effectiveness of commonly used aids to smoking cessation in England by using longitudinal data. Patients and Methods We conducted a prospective cohort study in 1560 adult smokers who participated in an English national household survey in the period from November 2006 to March 2012, responded to a 6-month follow-up survey, and made at least 1 quit attempt between the 2 measurements. The quitting method was classified as follows: (1) prescription medication (nicotine replacement therapy [NRT], bupropion, or varenicline) in combination with specialist behavioral support delivered by a National Health Service Stop Smoking Service; (2) prescription medication with brief advice; (3) NRT bought over the counter; (4) none of these. The primary outcome measure was self-reported abstinence up to the time of the 6-month follow-up survey, adjusted for key potential confounders including cigarette dependence. Results Compared with smokers using none of the cessation aids, the adjusted odds of remaining abstinent up to the time of the 6-month follow-up survey were 2.58 (95% CI, 1.48-4.52) times higher in users of prescription medication in combination with specialist behavioral support and 1.55 (95% CI, 1.11-2.16) times higher in users of prescription medication with brief advice. The use of NRT bought over the counter was associated with a lower odds of abstinence (odds ratio, 0.68; 95% CI, 0.49-0.94). Conclusion Prescription medication offered with specialist behavioral support and that offered with minimal behavioral support are successful methods of stopping cigarette smoking in England.

Type: Article
Title: Prospective cohort study of the effectiveness of smoking cessation treatments used in the "real world".
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.mayocp.2014.07.004
Publisher version: http://dx.doi.org/10.1016/j.mayocp.2014.07.004
Language: English
Additional information: PMCID: PMC4194355 Copyright © 2014 Mayo Foundation for Medical Education and Research. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/)
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
URI: https://discovery.ucl.ac.uk/id/eprint/1452060
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