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X-ray scatter signatures for normal and neoplastic breast tissues

Kidane, G; Speller, RD; Royle, GJ; Hanby, AM; (1999) X-ray scatter signatures for normal and neoplastic breast tissues. PHYS MED BIOL , 44 (7) 1791 - 1802.

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Abstract

Measurements of breast tissue scattering properties have been made in an energy dispersive x-ray diffraction system over the momentum transfer range of 0.70 to 3.50 nm(-1). One hundred samples of excised tissue have been used. Results from the diffraction system have been compared with the histological analysis for each individual sample, it has been found that tissue types can be characterized on the basis of the shape of the scatter spectrum and on its relative intensity. The shapes are significantly different between tissue types in the range 1.0 to 1.8 nm(-1) and suggest that if particular values of momentum transfer are monitored, a discriminating signal could be obtained. Analysis of the maximum intensity in the signature also reveals a change of up to a factor of 2 between adipose and fat-free tissues.

Type: Article
Title: X-ray scatter signatures for normal and neoplastic breast tissues
Keywords: COHERENT SCATTERING, CROSS-SECTIONS, FORM-FACTORS
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: http://discovery.ucl.ac.uk/id/eprint/145186
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