UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

The influence of fetal growth restriction and infection on the cerebral metabolic response to acute hypoxia.

Dixon, J.C.; (2005) The influence of fetal growth restriction and infection on the cerebral metabolic response to acute hypoxia. Doctoral thesis , University of London. Green open access

[img] Text
U592807.pdf

Download (9MB)

Abstract

Intrauterine growth restriction and infection are significant risk factors for neonatal hypoxic ischaemic encephalopathy in term neonates. It was hypothesised that these two factors increase the susceptibility of the fetal brain to hypoxic ischaemic damage by their influence on cerebral metabolism and development. Cerebral energy and structural metabolites in a late gestation in-ovo chick embryo model of acute hypoxia and fetal growth restriction were measured non invasive using proton and phosphorus Magnetic Resonance Spectroscopy. The influence of fetal growth restriction and acute hypoxia on cerebral metabolites was assessed. In addition, the individual and combined effects of growth restriction, acute hypoxia and systemic infection on morphological markers of neuronal injury were assessed.

Type: Thesis (Doctoral)
Title: The influence of fetal growth restriction and infection on the cerebral metabolic response to acute hypoxia.
Identifier: PQ ETD:592807
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Thesis digitised by Proquest
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Inst for Women's Health > Maternal and Fetal Medicine
URI: http://discovery.ucl.ac.uk/id/eprint/1445485
Downloads since deposit
92Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item