Liao, Y-F.; (2005) Timing of hard palate repair and facial growth in patients with unilateral cleft lip and palate. Doctoral thesis , University of London.

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Abstract

Lateral cephalometric radiographs from the growth archive of the Sri Lankan Cleft Lip and Palate Project were analyzed to elucidate the relationship between timing of hard palate repair and facial growth in patients with unilateral cleft lip and palate (UCLP). One hundred and twenty-five adult patients with nonsyndromic UCLP operated on at different ages for hard palate repair were recruited and their last cephalometric radiographs were used in the cross sectional analysis 104 patients with nonsyndromic UCLP operated on at different ages for hard palate repair and their 290 cephalometric radiographs were available in the longitudinal analysis. The design utilized statistical control for gender, age, and other covariates such as the timing and surgeon of lip repair as well as the technique and surgeon of hard palate repair. Results showed that the length of the alveolar maxilla (PMP-A, p = 0.05) and the anteroposterior alveolar jaw relation (ANB, p 0.05), were related to the timing of hard palate repair. These results suggest that in patients with UCLP late hard palate repair has a smaller adverse effect than early hard palate repair on the forward growth of the maxilla, and that timing of hard palate repair does not significantly affect the growth of the mandible.

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